Yes.
The e-mail marketing system does not use the Simple Mail Transfer Protocol ("SMTP"), but a custom network protocol ("SendEmails™") which is superior to the common SMTP protocol in means of speed, security and efficiency. Even if your ISP limits your outbound e-mail traffic, these restrictions will be bypassed. SendEmails™ will automatically probe for a working port and transfer all e-mails to a unique infrastructure of high-speed e-mail servers. Your ISP won't even notice, that you have sent e-mails, since an encrypted communication channel is used (SSL/TLSv1 encryption).